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Targeting ATFs in macrophages could be a potential therapeutic strategy Targeting ATFs in macrophages offers a promising therapeutic strategy, as these key transcription factors orchestrate diverse macrophage functional states, thereby enabling precise modulation of disease processes (Table III)

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Many patients experience gradual improvements, such as: Reduced pain and stiffness within 2 to 4 weeks Improved walking comfort and daily function Benefits that may last several months How many sessions are typically needed

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Chemoproteomics and chemical probes for target discovery

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